Human AXL Protein C-His-Avi Tag | Syd Labs BP005745
(悉得）Syd Labs 货号：BP005745 Human AXL Protein with the C-His-Avi Tag (人 AXL 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Pro449.
产品参数
| 货号 | BP005745 |
|---|---|
| 产品名称 | Human AXL Protein C-His-Avi Tag | Syd Labs BP005745 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1 |
| 物种 | Human |
| 来源 | The recombinant Human AXL Protein, (amino acids Ala26-Pro449) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P30530-1 |
| 产品标签 | C-His-Avi |
| 生物素化 | no |
| 确定序列 | Ala26-Pro449 |
| 分子量 | The recombinant Human AXL protein with the His-Avi tag at the C-terminus has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human AXL protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-AXL Antibody protein with the C-hFc tag with the EC50 of 15.5 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human AXL Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | > 95% as determined by Tris-Bis PAGE;> 95% as determined by SEC-HPLC |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human AXL Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human AXL Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005745: Human AXL Protein with the C-His-Avi Tag (人 AXL 蛋白 C-His-Avi 标签)
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
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