Cynomolgus Fc gamma RIII/CD16 Protein C-His Tag | Syd Labs BP005027
(悉得）Syd Labs 货号：BP005027 Cynomolgus Fc gamma RIII/CD16 Protein with the C-His Tag (食蟹猴 Fc γ RIII/CD16 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly17-Gln208.
产品参数
| 货号 | BP005027 |
|---|---|
| 产品名称 | Cynomolgus Fc gamma RIII/CD16 Protein C-His Tag | Syd Labs BP005027 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | IgG Fc receptor III; Fc-gamma RIII; FcRIII; FCGR3; CD16; CD16A; FCG3; FcgRIII; FCR-10; FCRIIIA; IGFR3; IMD20 |
| 物种 | Cynomolgus |
| 来源 | The recombinant Cynomolgus Fc gamma RIII/CD16 Protein, (amino acids Gly17-Gln208) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gly17-Gln208 |
| 分子量 | The recombinant Cynomolgus Fc gamma RIII/CD16 protein with the His tag at the C-terminus has a predicted MW of 23.1 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result. |
| 活性 | The affinity constant of 0.251 uM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Cynomolgus Fc gamma RIII/CD16 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Cynomolgus Fc gamma RIII/CD16 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Cynomolgus Fc gamma RIII/CD16 Protein performance should be determined experimentally by the investigator. |
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文献
BP005027: Cynomolgus Fc gamma RIII/CD16 Protein with the C-His Tag (食蟹猴 Fc γ RIII/CD16 蛋白 C-His 标签)
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set.
请记住我们的产品信息: 食蟹猴 Fc γ RIII/CD16 蛋白 （C-His 标签）BP005027 Syd Labs（Cynomolgus Fc gamma RIII/CD16 Protein with the C-His Tag）.
