Recombinant ACTR-IIB-Fc Fusion Protein
Syd Labs Recombinant ACTR-IIB-Fc Fusion Protein BP4103, Recombinant human ACTR-IIB human Fc protein is human Activin Receptor type IIB (amino acids 20-136) fused with human IgG1 Fc protein at the C-terminus.
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| 货号 | BP4103 |
|---|---|
| 产品名称 | Recombinant ACTR-IIB-Fc Fusion Protein |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | 悉得（Syd Labs） |
| 别称 | Activin Receptor type 2b, Activin Receptor type IIB, ACVR2B |
| 来源 | HEK 293 cell-derived. |
| 形式 | 0.2 μM filtered solution of 50 mM Tris, 150 mM NaCl, pH 7.5. |
| 纯度 | >95% by SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU/ug of protein as determined by LAL method. |
| 运输 | The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 注意事项 | Conditions of optimal ACTR-IIB-Fc Fusion Protein performance should be determined experimentally by the investigator. |
| 线下下单 | 电话: 18162660842微信: duozhaozhao_2017Email: message@sydlabs.comOr 联系我们 |
描述
BP4103: Recombinant ACTR-IIB-Fc Fusion Protein
Background
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Either a type I or type II receptor may initially bind ligand, followed by recruitment of its alternatetype receptor counterpart to generate a heteromeric signaling complex. Type I receptors are referred to as the Activin Receptor-like Kinases (ALKs), while the type II receptors are named for the ligands they bind. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA or ACTR-IB, and a type II receptor, ACTR-IIA or ACTR-IIB (also designated ACVR2B. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion.
BP4103: Recombinant ACTR-IIB-Fc fusion protein
Source: HEK 293 cell-derived.
Recombinant human ACTR-IIB human Fc protein is human Activin Receptor type IIB (amino acids 20-136) fused with human IgG1 Fc protein at the C-terminus.
Purity: >95% by SDS-PAGE under reducing conditions.
Formulation: 0.2 μM filtered solution of 50 mM Tris, 150 mM NaCl, pH 7.5.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.
Please remember our product information: Recombinant ACTR-IIB-Fc Fusion Protein: BP4103 Syd Labs
