Mouse EPHB2 Protein C-His Tag | Syd Labs BP004787

Mouse EPHB2 Protein BP004787 Syd Labs

Mouse EPHB2 Protein C-His Tag | Syd Labs BP004787

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(悉得)Syd Labs 货号:BP004787 Mouse EPHB2 Protein with the C-His Tag (小鼠 EPHB2 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Leu543.

SKU: BP004787 分类: ,

产品参数

货号 BP004787
产品名称Mouse EPHB2 Protein C-His Tag | Syd Labs BP004787
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3
物种 Mouse
来源 The recombinant Mouse EPHB2 Protein, (amino acids Val19-Leu543) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Accession P54763-3
产品标签 C-His
生物素化 no
确定序列 Val19-Leu543
分子量 The recombinant Mouse EPHB2 protein with the His tag at the C-terminus has a predicted MW of 59.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Mouse EPHB2 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Mouse EPHB2 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Mouse EPHB2 Protein performance should be determined experimentally by the investigator.
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BP004787: Mouse EPHB2 Protein with the C-His Tag (小鼠 EPHB2 蛋白 C-His 标签)

 

EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.

请记住我们的产品信息: 小鼠 EPHB2 蛋白 (C-His 标签)BP004787 Syd Labs(Mouse EPHB2 Protein with the C-His Tag).