Human PVRIG Protein BP005679 Syd Labs
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein BP005679 Syd Labs
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein (PVR-HM301)
Human PVRIG Protein (PVR-HM301)

Human PVRIG Protein C-mFc Tag | Syd Labs BP005679

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Human PVRIG Protein BP005679 Syd Labs

Human PVRIG Protein C-mFc Tag | Syd Labs BP005679

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(悉得）Syd Labs 货号：BP005679 Human PVRIG Protein with the C-mFc Tag (人 PVRIG 蛋白 C-mFc 标签) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Thr41-Asp171.

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SKU： BP005679 分类： ,

产品参数

货号 BP005679
产品名称Human PVRIG Protein C-mFc Tag | Syd Labs BP005679
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 C7orf15; CD112R; MGC104322; MGC138297; MGC2463; PVRIG; ALS2CR18; ALS2CR9; LPD; PREL-2; PREL2; RalGDS/AF-6; RMO1
物种 Human
来源 The recombinant Human PVRIG Protein, (amino acids Thr41-Asp171) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-mFc
生物素化 no
确定序列 Thr41-Asp171
分子量 The recombinant Human PVRIG protein with the mFc tag at the C-terminus has a predicted MW of 39.6 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human PVRIG protein with the C-mFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-PVRIG Antibody protein with the C-hFc tag with the EC50 of 8.0 ng/ml determined by ELISA. The affinity constant of 0.349 uM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human PVRIG Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human PVRIG Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human PVRIG Protein performance should be determined experimentally by the investigator.
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文献

BP005679: Human PVRIG Protein with the C-mFc Tag (人 PVRIG 蛋白 C-mFc 标签)

 

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.

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