Human PVRIG Protein BP003742 Syd Labs
Human PVRIG Protein (PVR-HM201)
Human PVRIG Protein (PVR-HM201)
Human PVRIG Protein BP003742 Syd Labs
Human PVRIG Protein (PVR-HM201)
Human PVRIG Protein (PVR-HM201)

Human PVRIG Protein C-hFc Tag | Syd Labs BP003742

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Human PVRIG Protein BP003742 Syd Labs

Human PVRIG Protein C-hFc Tag | Syd Labs BP003742

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(悉得）Syd Labs 货号：BP003742 Human PVRIG Protein with the C-hFc Tag (人 PVRIG 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr41-Asp171.

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Syd Labs, Inc.
SKU： BP003742 分类： ,

产品参数

货号 BP003742
产品名称Human PVRIG Protein C-hFc Tag | Syd Labs BP003742
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
物种 Human
来源 The recombinant Human PVRIG Protein, (amino acids Thr41-Asp171) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Accession Q6DKI7
产品标签 C-hFc
生物素化 no
确定序列 Thr41-Asp171
分子量 The recombinant Human PVRIG protein with the hFc tag at the C-terminus has a predicted MW of 40.42 kDa. Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human PVRIG protein with the C-hFc tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Anti-PVRIG Antibody protein with the C-hFc tag with the EC50 of 10.9 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human PVRIG Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human PVRIG Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human PVRIG Protein performance should be determined experimentally by the investigator.
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文献

BP003742: Human PVRIG Protein with the C-hFc Tag (人 PVRIG 蛋白 C-hFc 标签)

 

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.

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