Human NKG2A&CD94 Protein C-mFc Tag | Syd Labs BP005713
(悉得）Syd Labs 货号：BP005713 Human NKG2A&CD94 Protein with the C-mFc Tag (人 NKG2A&CD94 蛋白 C-mFc 标签) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Arg100-Leu233(NKG2A)&Ser34-Ile179(CD94).
产品参数
| 货号 | BP005713 |
|---|---|
| 产品名称 | Human NKG2A&CD94 Protein C-mFc Tag | Syd Labs BP005713 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD159a; NKG2A; NKG2-A; CD94; NKG2A&CD94 |
| 物种 | Human |
| 来源 | The recombinant Human NKG2A&CD94 Protein, (amino acids Arg100-Leu233(NKG2A) & Ser34-Ile179(CD94)) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-mFc |
| 生物素化 | no |
| 确定序列 | Arg100-Leu233(NKG2A) & Ser34-Ile179(CD94) |
| 分子量 | The recombinant Human NKG2A&CD94 protein with the mFc tag at the C-terminus has a predicted MW of 56.9 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human NKG2A&CD94 protein with the C-mFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-NKG2A Antibody protein with the C-hFc tag with the EC50 of 4.2 ng/ml determined by ELISA (QC Test). The affinity constant of 7.90 nM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human NKG2A&CD94 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human NKG2A&CD94 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human NKG2A&CD94 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005713: Human NKG2A&CD94 Protein with the C-mFc Tag (人 NKG2A&CD94 蛋白 C-mFc 标签)
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
请记住我们的产品信息: 人 NKG2A&CD94 蛋白 （C-mFc 标签）BP005713 Syd Labs（Human NKG2A&CD94 Protein with the C-mFc Tag）.
