Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein C-His-Avi Tag | Syd Labs BP005465
(悉得）Syd Labs 货号：BP005465 Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein with the C-His-Avi Tag (人整合素 alpha 5 beta 1 （ITGA5&ITGB1） 异二聚体蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe42-Tyr995(ITGA5) acidic tail&Gln21-Asp728(ITGB1) basic tail.
产品参数
| 货号 | BP005465 |
|---|---|
| 产品名称 | Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein C-His-Avi Tag | Syd Labs BP005465 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | Integrin alpha 5 beta 1; VLA-5; ITGA5&ITGB1 |
| 物种 | Human |
| 来源 | The recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, (amino acids Phe42-Tyr995(ITGA5) acidic tail & Gln21-Asp728(ITGB1) basic tail) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P08648(ITGA5)&P05556-1(ITGB1) |
| 产品标签 | C-His-Avi |
| 生物素化 | no |
| 确定序列 | Phe42-Tyr995(ITGA5)acidic tail & Gln21-Asp728(ITGB1)basic tail |
| 分子量 | The recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer protein with the His-Avi tag at the C-terminus has a predicted MW of 111.8 kDa (ITGA5)&83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 100-140 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human ITGA5&ITGB1 protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-ITGA5&ITGB1 Antibody protein with the C-hFc tag with the EC50 of 16.2 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005465: Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein with the C-His-Avi Tag (人整合素 alpha 5 beta 1 （ITGA5&ITGB1） 异二聚体蛋白 C-His-Avi 标签)
Integrin alpha 5/ beta 1, also known as VLA-5, is a widely expressed non-covalent heterodimer of a 160 kDa alpha 5 and a 130 kDa beta 1 Integrin subunit.Alpha 5/ beta 1 is up‑regulated on tumor vasculature and promotes angiogenesis.
请记住我们的产品信息: 人整合素 alpha 5 beta 1 （ITGA5&ITGB1） 异二聚体蛋白 （C-His-Avi 标签）BP005465 Syd Labs（Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein with the C-His-Avi Tag）.
