Human ILDR2 Protein C-hFc Tag | Syd Labs BP005002
(悉得）Syd Labs 货号：BP005002 Human ILDR2 Protein with the C-hFc Tag (人 ILDR2 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.
产品参数
| 货号 | BP005002 |
|---|---|
| 产品名称 | Human ILDR2 Protein C-hFc Tag | Syd Labs BP005002 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | ILDR2; C1orf32; dJ782G3.1; RP4-782G3.2 |
| 物种 | Human |
| 来源 | The recombinant Human ILDR2 Protein, (amino acids Leu21-Met184) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Leu21-Met184 |
| 分子量 | The recombinant Human ILDR2 protein with the hFc tag at the C-terminus has a predicted MW of 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human ILDR2 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | > 95% as determined by Tris-Bis PAGE;> 92% as determined by HPLC |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human ILDR2 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human ILDR2 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005002: Human ILDR2 Protein with the C-hFc Tag (人 ILDR2 蛋白 C-hFc 标签)
Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.
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