Human IL-10 R alpha Protein BP004615 Syd Labs
Human IL-10 R alpha Protein (IL1-HM4RA)
Human IL-10 R alpha Protein (IL1-HM4RA)
Human IL-10 R alpha Protein (IL1-HM4RA)
Human IL-10 R alpha Protein BP004615 Syd Labs
Human IL-10 R alpha Protein (IL1-HM4RA)
Human IL-10 R alpha Protein (IL1-HM4RA)
Human IL-10 R alpha Protein (IL1-HM4RA)

Human IL-10 R alpha Protein C-His-Avi Tag | Syd Labs BP004615

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Human IL-10 R alpha Protein BP004615 Syd Labs

Human IL-10 R alpha Protein C-His-Avi Tag | Syd Labs BP004615

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Syd Labs 货号：BP004615 Human IL-10 R alpha Protein with the C-His-Avi Tag (人 IL-10 R α 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-Asn235.

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SKU： BP004615 分类： ,

产品参数

货号 BP004615
产品名称Human IL-10 R alpha Protein C-His-Avi Tag | Syd Labs BP004615
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 IL-10RA; IL10RA; IL10R; IL-10R1; IL-10R subunit 1; CDw210a; HIL-10R; IBD28; IL-10 R alpha
物种 Human
来源 The recombinant Human IL-10 R alpha Protein, (amino acids His22-Asn235) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His-Avi
生物素化 no
确定序列 His22-Asn235
分子量 The recombinant Human IL-10 R alpha protein with the His-Avi tag at the C-terminus has a predicted MW of 27 kDa. Due to glycosylation, the protein migrates to 40-48 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human IL-10 protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human IL-10 R alpha protein with the C-His tag with the EC50 of 48.4 ng/ml determined by ELISA (QC Test). The affinity constant of 0.13 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human IL-10 R alpha Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human IL-10 R alpha Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human IL-10 R alpha Protein performance should be determined experimentally by the investigator.
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文献

BP004615: Human IL-10 R alpha Protein with the C-His-Avi Tag (人 IL-10 R α 蛋白 C-His-Avi 标签)

 

The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne’s disease (JD). JD is a chronic enteritis in cattle caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is responsible for significant economic losses to the dairy industry. Several candidate genes including IL10RA have been found to be associated with JD.

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