Human IGFBP-3R Protein BP004647 Syd Labs
Human IGFBP-3R Protein BP004647 Syd Labs

Human IGFBP-3R Protein C-hFc Tag | Syd Labs BP004647

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Human IGFBP-3R Protein BP004647 Syd Labs

Human IGFBP-3R Protein C-hFc Tag | Syd Labs BP004647

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Syd Labs 货号：BP004647 Human IGFBP-3R Protein with the C-hFc Tag (人 IGFBP-3R 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser39-Arg204.

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Syd Labs, Inc.
SKU： BP004647 分类： ,

产品参数

货号 BP004647
产品名称Human IGFBP-3R Protein C-hFc Tag | Syd Labs BP004647
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 IGFBP-3R; GFBP3R; LOC124446; TMEM219
物种 Human
来源 The recombinant Human IGFBP-3R Protein, (amino acids Ser39-Arg204) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-hFc
生物素化 no
确定序列 Ser39-Arg204
分子量 The recombinant Human IGFBP-3R protein with the hFc tag at the C-terminus has a predicted MW of 44.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human IGFBP-3R Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human IGFBP-3R Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human IGFBP-3R Protein performance should be determined experimentally by the investigator.
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文献

BP004647: Human IGFBP-3R Protein with the C-hFc Tag (人 IGFBP-3R 蛋白 C-hFc 标签)

 

Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.

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