Human GPC3 (438-554) Protein-VLP | Syd Labs BP003780
(悉得)Syd Labs 货号:BP003780 Human GPC3 (438-554) Protein-VLP (人 GPC3 (438-554) 蛋白-VLP) is expressed from HEK293.It contains Arg438-Asn554.
产品参数
| 货号 | BP003780 |
|---|---|
| 产品名称 | Human GPC3 (438-554) Protein-VLP | Syd Labs BP003780 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Human |
| 来源 | The recombinant Human GPC3 (438-554) Protein-VLP, (amino acids Arg438-Asn554) , was produced in HEK 293 cells. |
| 生物素化 | no |
| 确定序列 | Arg438-Asn554 |
| 分子量 | The recombinant Human GPC3 (438-554) Protein-VLP protein has a predicted MW of 21.5 kDa. |
| 活性 | Immobilized recombinant Human GPC3 (438-554) VLP at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-GPC3 Antibody, hFc tag with the EC50 of 9.7 ng/ml determined by ELISA. |
| Form | Liquid |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human GPC3 (438-554) Protein-VLP in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human GPC3 (438-554) Protein-VLP is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human GPC3 (438-554) Protein-VLP performance should be determined experimentally by the investigator. |
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文献
BP003780: Human GPC3 (438-554) Protein-VLP (人 GPC3 (438-554) 蛋白-VLP)
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed.
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