Human GPA Protein C-hFc Tag | Syd Labs BP004908

Human GPA Protein BP004908 Syd Labs

Human GPA Protein C-hFc Tag | Syd Labs BP004908

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(悉得)Syd Labs 货号:BP004908 Human GPA Protein with the C-hFc Tag (人 GPA 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser20-Glu91.

SKU: BP004908 分类: ,

产品参数

货号 BP004908
产品名称Human GPA Protein C-hFc Tag | Syd Labs BP004908
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Glycophorin-A; PAS-2; CD235a; glycophorin Erik; glycophorin MiI; glycophorin MiIII; glycophorin MiV; glycophorin MiX; glycophorin SAT; GPA; GPErik; GpMiIII; GPSAT; GYPA; HGpMiIII; HGpMiV; HGpMiX; HGpMiXI; HGpSta(C); MNS; CD235a; MN
物种 Human
来源 The recombinant Human GPA Protein, (amino acids Ser20-Glu91) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Accession P02724-1
产品标签 C-hFc
生物素化 no
确定序列 Ser20-Glu91
分子量 The recombinant Human GPA protein with the hFc tag at the C-terminus has a predicted MW of 34.7 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.
活性 The affinity constant of 0.72 uM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human GPA Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human GPA Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human GPA Protein performance should be determined experimentally by the investigator.
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文献

BP004908: Human GPA Protein with the C-hFc Tag (人 GPA 蛋白 C-hFc 标签)

 

Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes the rapidly progressive disorder one of the most challenging dilemmas in clinical medicine.The ultimate goal is an improved prognosis through outcome measures which assesses the disease control with minimal adverse effects of intensive immunosuppressive regimens, an integral part of the clinical approach to improve the quality of life of GPA patients.

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