Human FCRL2/IRTA4 Protein C-His Tag | Syd Labs BP004337
(悉得)Syd Labs 货号:BP004337 Human FCRL2/IRTA4 Protein with the C-His Tag (人 FCRL2/IRTA4 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Val401.
产品参数
| 货号 | BP004337 |
|---|---|
| 产品名称 | Human FCRL2/IRTA4 Protein C-His Tag | Syd Labs BP004337 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | FcR-like protein 2; FcRL2; FCRH2; IFGP4; IRTA4; FCRL2; CD307b; FCRH2SPAP1B; IRTA4SPAP1C; SPAP1; SPAP1A |
| 物种 | Human |
| 来源 | The recombinant Human FCRL2/IRTA4 Protein, (amino acids Leu20-Val401) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Leu20-Val401 |
| 分子量 | The recombinant Human FCRL2/IRTA4 protein with the His tag at the C-terminus has a predicted MW of 42.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human FCRL2 protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-FCRL2 Antibody protein with the C-hFc tag with the EC50 of 0.13 ug/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human FCRL2/IRTA4 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | It is recommended to reconstitute the lyophilized recombinant Human FCRL2/IRTA4 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human FCRL2/IRTA4 Protein performance should be determined experimentally by the investigator. |
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文献
BP004337: Human FCRL2/IRTA4 Protein with the C-His Tag (人 FCRL2/IRTA4 蛋白 C-His 标签)
Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation; P < 0.0001) and cells of other hematological diseases.
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