Human Fc gamma RIIIB/CD16b (NA1) Protein C-His Tag | Syd Labs BP004235
(悉得）Syd Labs 货号：BP004235 Human Fc gamma RIIIB/CD16b (NA1) Protein with the C-His Tag (人 Fc γ RIIIB/CD16b （NA1） 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly17-Ser200(NA1).
产品参数
| 货号 | BP004235 |
|---|---|
| 产品名称 | Human Fc gamma RIIIB/CD16b (NA1) Protein C-His Tag | Syd Labs BP004235 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD16; CD16b antigen; CD16b（NA1); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc fragment of IgG, low affinity IIIb, receptor for (CD16); Fc gamma RIIIB; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; Fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcgRIIIB; FcR-10; fcRIII; FCRIIIB; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B |
| 物种 | Human |
| 来源 | The recombinant Human Fc gamma RIIIB/CD16b (NA1) Protein, (amino acids Gly17-Ser200(NA1)) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gly17-Ser200(NA1) |
| 分子量 | The recombinant Human Fc gamma RIIIB/CD16b (NA1) protein with the His tag at the C-terminus has a predicted MW of 22.52 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| 活性 | The affinity constant of 8.55 uM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human Fc gamma RIIIB/CD16b (NA1) Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human Fc gamma RIIIB/CD16b (NA1) Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human Fc gamma RIIIB/CD16b (NA1) Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004235: Human Fc gamma RIIIB/CD16b (NA1) Protein with the C-His Tag (人 Fc γ RIIIB/CD16b （NA1） 蛋白 C-His 标签)
Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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