Human DDR1 Protein BP004392 Syd Labs
Human DDR1 Protein (DDR-HM1R1)
Human DDR1 Protein (DDR-HM1R1)
Human DDR1 Protein (DDR-HM1R1)
Human DDR1 Protein BP004392 Syd Labs
Human DDR1 Protein (DDR-HM1R1)
Human DDR1 Protein (DDR-HM1R1)
Human DDR1 Protein (DDR-HM1R1)

Human DDR1 Protein C-His Tag | Syd Labs BP004392

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Human DDR1 Protein BP004392 Syd Labs

Human DDR1 Protein C-His Tag | Syd Labs BP004392

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(悉得）Syd Labs 货号：BP004392 Human DDR1 Protein with the C-His Tag (人 DDR1 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Asp21-Ala417.

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SKU： BP004392 分类： ,

产品参数

货号 BP004392
产品名称Human DDR1 Protein C-His Tag | Syd Labs BP004392
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 HGK2; MCK-10; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; CD167a; EC 2.7.10.1
物种 Human
来源 The recombinant Human DDR1 Protein, (amino acids Asp21-Ala417) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His
生物素化 no
确定序列 Asp21-Ala417
分子量 The recombinant Human DDR1 protein with the His tag at the C-terminus has a predicted MW of 45.1 kDa. Due to glycosylation, the protein migrates to 63-67 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human DDR1 protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-DDR1 Antibody protein with the C-hFc tag with the EC50 of 5.9 ng/ml determined by ELISA (QC Test). The affinity constant of 0.806 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human DDR1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human DDR1 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human DDR1 Protein performance should be determined experimentally by the investigator.
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文献

BP004392: Human DDR1 Protein with the C-His Tag (人 DDR1 蛋白 C-His 标签)

 

Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1’s biology is elusive, with unknown downstream activation pathways; however, it may act as a mediator of the stromal-epithelial interaction, potentially controlling the activation state of the resident quiescent fibroblasts.

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