Human CD96/TACTILE Protein BP004641 Syd Labs
Human CD96/TACTILE Protein (CD9-HM396)
Human CD96/TACTILE Protein (CD9-HM396)
Human CD96/TACTILE Protein BP004641 Syd Labs
Human CD96/TACTILE Protein (CD9-HM396)
Human CD96/TACTILE Protein (CD9-HM396)

Human CD96/TACTILE Protein C-mFc Tag | Syd Labs BP004641

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Human CD96/TACTILE Protein BP004641 Syd Labs

Human CD96/TACTILE Protein C-mFc Tag | Syd Labs BP004641

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(悉得）Syd Labs 货号：BP004641 Human CD96/TACTILE Protein with the C-mFc Tag (人 CD96/TACTILE 蛋白 C-mFc 标签) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Val22-Met503.

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Syd Labs, Inc.
SKU： BP004641 分类： ,

产品参数

货号 BP004641
产品名称Human CD96/TACTILE Protein C-mFc Tag | Syd Labs BP004641
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CD96 molecule; CD96; DKFZp667E2122; TACTILE
物种 Human
来源 The recombinant Human CD96/TACTILE Protein, (amino acids Val22-Met503) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
Accession P40200-2
产品标签 C-mFc
生物素化 no
确定序列 Val22-Met503
分子量 The recombinant Human CD96/TACTILE protein with the mFc tag at the C-terminus has a predicted MW of 79.8 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human CD96 protein with the C-mFc tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human CD155 protein with the C-hFc tag with the EC50 of 0.21 ug/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human CD96/TACTILE Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human CD96/TACTILE Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human CD96/TACTILE Protein performance should be determined experimentally by the investigator.
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文献

BP004641: Human CD96/TACTILE Protein with the C-mFc Tag (人 CD96/TACTILE 蛋白 C-mFc 标签)

 

The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

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