Human ASPH Protein N-His Tag | Syd Labs BP004318
(悉得)Syd Labs 货号:BP004318 Human ASPH Protein with the N-His Tag (人 ASPH 蛋白 N-His 标签) is expressed from E.coli with His tag at the N-Terminus.It contains Ile341-Ile758.
产品参数
| 货号 | BP004318 |
|---|---|
| 产品名称 | Human ASPH Protein N-His Tag | Syd Labs BP004318 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | Aspartate beta-hydroxylase; ASP beta-hydroxylase; Asph; Bah |
| 物种 | Human |
| 来源 | The recombinant Human ASPH Protein, (amino acids Ile341-Ile758) fused with a His tag at the N-terminus, was produced in E.coli cells. |
| 产品标签 | N-His |
| 生物素化 | no |
| 确定序列 | Ile341-Ile758 |
| 分子量 | The recombinant Human ASPH protein with the His tag at the N-terminus has a predicted MW of 49.2 kDa same as Tris-Bis PAGE result. |
| Form | Liquid |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human ASPH Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human ASPH Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human ASPH Protein performance should be determined experimentally by the investigator. |
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文献
BP004318: Human ASPH Protein with the N-His Tag (人 ASPH 蛋白 N-His 标签)
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis.
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