Human 4-1BB Ligand/TNFSF9 Trimer Protein N-monomeric hFc Tag | Syd Labs BP005298

Human 4-1BB Ligand/TNFSF9 Trimer Protein BP005298 Syd Labs

Human 4-1BB Ligand/TNFSF9 Trimer Protein N-monomeric hFc Tag | Syd Labs BP005298

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(悉得)Syd Labs 货号:BP005298 Human 4-1BB Ligand/TNFSF9 Trimer Protein with the N-monomeric hFc Tag (人 4-1BB 配体/TNFSF9 三聚体蛋白 N-单体 hFc 标签) is expressed from HEK293 with monomeric hFc tag at the N-Terminus.It contains Arg71-Glu254.

SKU: BP005298 分类: ,

产品参数

货号 BP005298
产品名称Human 4-1BB Ligand/TNFSF9 Trimer Protein N-monomeric hFc Tag | Syd Labs BP005298
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9
物种 Human
来源 The recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein, (amino acids Arg71-Glu254) fused with a monomeric hFc tag at the N-terminus, was produced in HEK 293 cells.
Accession P41273
产品标签 N-monomeric hFc
生物素化 no
确定序列 Arg71-Glu254
分子量 The recombinant Human 4-1BB Ligand/TNFSF9 Trimer protein with the monomeric hFc tag at the N-terminus has a predicted MW of 84.3 kDa same as Tris-Bis PAGE result.
活性 Immobilized recombinant Human 4-1BB protein with the N-monomeric hFc tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human 4-1BB Ligand Trimer protein with the N-hFc tag with the EC50 of 3.3 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein performance should be determined experimentally by the investigator.
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文献

BP005298: Human 4-1BB Ligand/TNFSF9 Trimer Protein with the N-monomeric hFc Tag (人 4-1BB 配体/TNFSF9 三聚体蛋白 N-单体 hFc 标签)

 

The 4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. 4-1BB ligand (4-1BBL) is an inducible molecule present on several APC types, including B cells, macrophages and DCs.4-1BB:4-1BBL pathway seems to amplify the existing costimulatory signals, even if the engagement of 4-1BB in the presence of a strong TCR signaling can induce IL-2 production in a CD28-independent manner.

请记住我们的产品信息: 人 4-1BB 配体/TNFSF9 三聚体蛋白 (N-单体 hFc 标签)BP005298 Syd Labs(Human 4-1BB Ligand/TNFSF9 Trimer Protein with the N-monomeric hFc Tag).