Cynomolgus IL-13 Protein N-His Tag | Syd Labs BP003709
(悉得）Syd Labs 货号：BP003709 Cynomolgus IL-13 Protein with the N-His Tag (食蟹猴 IL-13 蛋白 N-His 标签) is expressed from HEK293 with His tag at the N-Terminus.It contains Ser19-Asn132.
产品参数
| 货号 | BP003709 |
|---|---|
| 产品名称 | Cynomolgus IL-13 Protein N-His Tag | Syd Labs BP003709 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Cynomolgus |
| 来源 | The recombinant Cynomolgus IL-13 Protein, (amino acids Ser19-Asn132) fused with a His tag at the N-terminus, was produced in HEK 293 cells. |
| 产品标签 | N-His |
| 生物素化 | no |
| 确定序列 | Ser19-Asn132 |
| 分子量 | The recombinant Cynomolgus IL-13 protein with the His tag at the N-terminus has a predicted MW of 13.59 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Cynomolgus IL-13 protein with the N-His tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human IL-13Ra2 protein with the N-hFc tag with the EC50 of 1.72 ug/ml determined by ELISA (QC Test). The affinity constant of 21.16 nM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Cynomolgus IL-13 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Cynomolgus IL-13 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Cynomolgus IL-13 Protein performance should be determined experimentally by the investigator. |
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文献
BP003709: Cynomolgus IL-13 Protein with the N-His Tag (食蟹猴 IL-13 蛋白 N-His 标签)
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages.
请记住我们的产品信息: 食蟹猴 IL-13 蛋白 （N-His 标签）BP003709 Syd Labs（Cynomolgus IL-13 Protein with the N-His Tag）.
