Cynomolgus GDF15 Protein N-hFc Tag | Syd Labs BP005008
(悉得）Syd Labs 货号：BP005008 Cynomolgus GDF15 Protein with the N-hFc Tag (食蟹猴 GDF15 蛋白 N-hFc 标签) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala197-Val308.
产品参数
| 货号 | BP005008 |
|---|---|
| 产品名称 | Cynomolgus GDF15 Protein N-hFc Tag | Syd Labs BP005008 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta |
| 物种 | Cynomolgus |
| 来源 | The recombinant Cynomolgus GDF15 Protein, (amino acids Ala197-Val308) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells. |
| 产品标签 | N-hFc |
| 生物素化 | no |
| 确定序列 | Ala197-Val308 |
| 分子量 | The recombinant Cynomolgus GDF15 protein with the hFc tag at the N-terminus has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Cynomolgus GFRAL protein with the N-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Cynomolgus GDF15 protein with the N-hFc tag with the EC50 of 3.6 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Cynomolgus GDF15 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Cynomolgus GDF15 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
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文献
BP005008: Cynomolgus GDF15 Protein with the N-hFc Tag (食蟹猴 GDF15 蛋白 N-hFc 标签)
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.
请记住我们的产品信息: 食蟹猴 GDF15 蛋白 （N-hFc 标签）BP005008 Syd Labs（Cynomolgus GDF15 Protein with the N-hFc Tag）.
