Cynomolgus CTLA-4/CD152 Protein BP005158 Syd Labs
Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
Cynomolgus CTLA-4/CD152 Protein BP005158 Syd Labs
Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)

Cynomolgus CTLA-4/CD152 Protein C-His Tag | Syd Labs BP005158

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Cynomolgus CTLA-4/CD152 Protein BP005158 Syd Labs

Cynomolgus CTLA-4/CD152 Protein C-His Tag | Syd Labs BP005158

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(悉得）Syd Labs 货号：BP005158 Cynomolgus CTLA-4/CD152 Protein with the C-His Tag (食蟹猴 CTLA-4/CD152 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Ala37-Ser160.

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SKU： BP005158 分类： ,

产品参数

货号 BP005158
产品名称Cynomolgus CTLA-4/CD152 Protein C-His Tag | Syd Labs BP005158
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CTLA4; CD152; ICOS; CELIAC3; GRD4; GSE; ALPS5; IDDM12
物种 Cynomolgus
来源 The recombinant Cynomolgus CTLA-4/CD152 Protein, (amino acids Ala37-Ser160) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His
生物素化 no
确定序列 Ala37-Ser160
分子量 The recombinant Cynomolgus CTLA-4/CD152 protein with the His tag at the C-terminus has a predicted MW of 14.4 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Cynomolgus CTLA-4 protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-CTLA-4 Antibody protein with the C-hFc tag with the EC50 of 11.2 ng/ml determined by ELISA (QC Test). The affinity constant of 9.90 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Cynomolgus CTLA-4/CD152 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Cynomolgus CTLA-4/CD152 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Cynomolgus CTLA-4/CD152 Protein performance should be determined experimentally by the investigator.
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文献

BP005158: Cynomolgus CTLA-4/CD152 Protein with the C-His Tag (食蟹猴 CTLA-4/CD152 蛋白 C-His 标签)

 

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an “off” switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.

请记住我们的产品信息: 食蟹猴 CTLA-4/CD152 蛋白 （C-His 标签）BP005158 Syd Labs（Cynomolgus CTLA-4/CD152 Protein with the C-His Tag）.