Cynomolgus AXL Protein BP004386 Syd Labs
Cynomolgus AXL Protein (AXL-CM102)
Cynomolgus AXL Protein (AXL-CM102)
Cynomolgus AXL Protein (AXL-CM102)
Cynomolgus AXL Protein BP004386 Syd Labs
Cynomolgus AXL Protein (AXL-CM102)
Cynomolgus AXL Protein (AXL-CM102)
Cynomolgus AXL Protein (AXL-CM102)

Cynomolgus AXL Protein C-His Tag | Syd Labs BP004386

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Proteinase K Solution, PCR Grade (20 mg/ml): MB112 Syd Labs Proteinase K Solution, PCR Grade (20 mg/ml)
Cynomolgus AXL Protein BP004386 Syd Labs

Cynomolgus AXL Protein C-His Tag | Syd Labs BP004386

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(悉得）Syd Labs 货号：BP004386 Cynomolgus AXL Protein with the C-His Tag (食蟹猴 AXL 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Pro449.

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SKU： BP004386 分类： ,

产品参数

货号 BP004386
产品名称Cynomolgus AXL Protein C-His Tag | Syd Labs BP004386
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1
物种 Cynomolgus
来源 The recombinant Cynomolgus AXL Protein, (amino acids Glu33-Pro449) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His
生物素化 no
确定序列 Glu33-Pro449
分子量 The recombinant Cynomolgus AXL protein with the His tag at the C-terminus has a predicted MW of 46.3 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Cynomolgus AXL protein with the C-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-AXL Antibody protein with the C-hFc tag with the EC50 of 8.8 ng/ml determined by ELISA (QC Test). The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Cynomolgus AXL Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Cynomolgus AXL Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Cynomolgus AXL Protein performance should be determined experimentally by the investigator.
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文献

BP004386: Cynomolgus AXL Protein with the C-His Tag (食蟹猴 AXL 蛋白 C-His 标签)

 

Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.

请记住我们的产品信息: 食蟹猴 AXL 蛋白 （C-His 标签）BP004386 Syd Labs（Cynomolgus AXL Protein with the C-His Tag）.