Canine PDGF R beta/CD140b Protein C-His Tag | Syd Labs BP003520
(悉得）Syd Labs 货号：BP003520 Canine PDGF R beta/CD140b Protein with the C-His Tag (犬 PDGF R β/CD140b 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly32-Val532.
产品参数
| 货号 | BP003520 |
|---|---|
| 产品名称 | Canine PDGF R beta/CD140b Protein C-His Tag | Syd Labs BP003520 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Canine |
| 来源 | The recombinant Canine PDGF R beta/CD140b Protein, (amino acids Gly32-Val532) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gly32-Val532 |
| 分子量 | The recombinant Canine PDGF R beta/CD140b Protein, (amino acids Gly32-Val532) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 活性 | The affinity constant of 0.203 uM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Canine PDGF R beta/CD140b Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Canine PDGF R beta/CD140b Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
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文献
BP003520: Canine PDGF R beta/CD140b Protein with the C-His Tag (犬 PDGF R β/CD140b 蛋白 C-His 标签)
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
请记住我们的产品信息: 犬 PDGF R β/CD140b 蛋白 （C-His 标签）BP003520 Syd Labs（Canine PDGF R beta/CD140b Protein with the C-His Tag）.
