Biotinylated Human DLL4 Protein C-His-Avi Tag | Syd Labs BP005036
(悉得)Syd Labs 货号:BP005036 Biotinylated Human DLL4 Protein with the C-His-Avi Tag (生物素化人 DLL4 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser27-Pro524.
产品参数
| 货号 | BP005036 |
|---|---|
| 产品名称 | Biotinylated Human DLL4 Protein C-His-Avi Tag | Syd Labs BP005036 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | DLL4; MGC126344; notch ligand DLL4; Delta4; Delta-like 4 |
| 物种 | Human |
| 来源 | The recombinant Biotinylated Human DLL4 Protein, (amino acids Ser27-Pro524) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His-Avi |
| 生物素化 | yes |
| 确定序列 | Ser27-Pro524 |
| 分子量 | The recombinant Biotinylated Human DLL4 protein with the His-Avi tag at the C-terminus has a predicted MW of 55.7 kDa. Due to glycosylation, the protein migrates to 62-68 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Anti-DLL4 Antibody protein with the C-His-Avi tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human DLL4 protein with the C-His tag with the EC50 of 0.21 ug/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Biotinylated Human DLL4 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Biotinylated Human DLL4 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Biotinylated Human DLL4 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品,不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题,欢迎随时联系Syd Labs国内市场推广合作伙伴:武汉多找找科技有限公司,企业微信:duozhaozhao2024 联系电话:18162581039(龙经理) |
文献
BP005036: Biotinylated Human DLL4 Protein with the C-His-Avi Tag (生物素化人 DLL4 蛋白 C-His-Avi 标签)
Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.
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