Phospho-TBK1/NAK-S172 Rabbit mAb

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Phospho-TBK1/NAK-S172 Rabbit mAb

In stock

NAK; T2K; IIAE8; FTDALS4

SKU: AP1418 分类: ,
货号 AP1418
产品名称Phospho-TBK1/NAK-S172 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 NAK; T2K; IIAE8; FTDALS4
基因名称 TBK1
蛋白名 TBK1
Uniprot/Swissprot ID Q9UHD2
Entrez GeneID 29110
克隆号 ARC57906
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response.

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