Phospho-Met-Y1234/Y1235 Rabbit mAb
DA11; HGFR; AUTS9; RCCP2; c-Met; DFNB97
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货号 | AP1339 |
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产品名称 | Phospho-Met-Y1234/Y1235 Rabbit mAb |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | DA11; HGFR; AUTS9; RCCP2; c-Met; DFNB97 |
基因名称 | MET |
蛋白名 | MET |
Uniprot/Swissprot ID | P08581 |
Entrez GeneID | 4233 |
克隆号 | ARC54652 |
克隆性 | Monoclonal |
来源 | Rabbit |
反应性 | Human, Mouse, Rat |
偶联 | Unconjugated |
注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com |
描述
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.