Phospho-Met-Y1234/Y1235 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-Met-Y1234/Y1235 Rabbit mAb

In stock

DA11; HGFR; AUTS9; RCCP2; c-Met; DFNB97

SKU: AP1339 分类: ,
货号 AP1339
产品名称Phospho-Met-Y1234/Y1235 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 DA11; HGFR; AUTS9; RCCP2; c-Met; DFNB97
基因名称 MET
蛋白名 MET
Uniprot/Swissprot ID P08581
Entrez GeneID 4233
克隆号 ARC54652
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
线下下单 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com

描述

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.

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