Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg

Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg

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Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg. Pertuzumab biosimilar CHO stable cell line is available for licensing to manufacture the pertuzumab biosimilar protein.The research grade pertuzumab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available.

SKU: C006P.LA.05 分类: ,
货号 C006P.LA.05
产品名称Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 Anti-ErbB-2 Humanized Monoclonal Antibody, Anti-c-neu Humanized Monoclonal Antibody
概述 Recombinant humanized IgG1 Monoclonal Antibody.
同种型 Human IgG1 kappa.
来源 The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.
特异性 The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.
应用 ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.
抗体形式 0.2 uM filtered solution, pH 6.0, no stabilizers or preservatives.
内毒素 < 0.05 EU per 1 mg of the protein by the LAL method.
纯度 >95% by SDS-PAGE under reducing conditions and HPLC.
运输 The Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与存储 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
注意事项 Pertuzumab biosimilar CHO stable cell line is available for licensing to manufacture the pertuzumab biosimilar protein.The research grade pertuzumab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available.
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描述

C006P.LA.05: Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg

Recombinant humanized IgG1 Monoclonal Antibody.

Background

Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.

Syd Labs also provides the following anti-ErbB/HER antibody biosimilar proteins:
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)

Syd Labs also provides the following research grade antibody biosimilar proteins:
Bevacizumab Biosimilar, research grade (VEGF-A)
Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Infliximab biosimilar, research grade (TNF alpha)
Adalimumab biosimilar, research grade (TNF alpha)
Rituximab biosimilar, research grade (CD20)
Denosumab biosimilar, research grade (RANKL, RANK ligand, OPGL, TNFSF11, CD254, TRANCE, ODF)
Palivizumab Biosimilar, research grade (RSV)
Omalizumab biosimilar, research grade (IgE)
Eculizumab biosimilar, research grade (C5)

Please remember our product information: Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant, Endotoxin 0.05 EU/mg: C006P.LA.05 Syd Labs

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