p53 Monoclonal Antibody
Conditions of optimal p53 monoclonal antibody performance should be determined experimentally by the investigator.
产品参数
| 货号 | PA000071-MA1078 |
|---|---|
| 产品名称 | p53 Monoclonal Antibody |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | ntigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53 |
| 克隆号 | IMD-53. |
| 同种型 | Mouse IgG2a. |
| 特异性 | Human. No cross reactivity with other proteins. |
| 反应性 | Human. |
| 免疫源 | Recombinant human wild-type p53 protein. |
| 纯化 | Purified by the goat anti-mouse IgG affinity chromatography. |
| 抗体形式 | Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative. |
| 稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| 注意事项 | Conditions of optimal p53 antibody performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
文献
PA000071-MA1078: p53 Monoclonal Antibody
Background
The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis
Other p53 Antibodies:
p53 Polyclonal Antibody
p53 Polyclonal Antibody
p53 (Acetyl-Lys317) Polyclonal Antibody
p53 (Ab-6) Polyclonal Antibody
p53 (Ab-392) Polyclonal Antibody
p53 (Ab-382) Polyclonal Antibody
p53 (Ab-18) Polyclonal Antibody
p53 Proteins:
Recombinant Human Cellular tumor antigen p53 Protein
Recombinant Human Cellular tumor antigen p53 Protein
