Mouse Thyroid Peroxidase Protein C-His Tag | Syd Labs BP004450
(悉得）Syd Labs 货号：BP004450 Mouse Thyroid Peroxidase Protein with the C-His Tag (小鼠甲状腺过氧化物酶蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly32-Arg834.
产品参数
| 货号 | BP004450 |
|---|---|
| 产品名称 | Mouse Thyroid Peroxidase Protein C-His Tag | Syd Labs BP004450 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | TPO; THPO; MGC163194; MGDF; MKCSF; ML; MPLLG; THCYT1; MGDFC-mpl ligand; MK-CSF; MPL ligand; Thrombopoietin; TPOMKCSF |
| 物种 | Mouse |
| 来源 | The recombinant Mouse Thyroid Peroxidase Protein, (amino acids Gly32-Arg834) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P35419 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gly32-Arg834 |
| 分子量 | The recombinant Mouse Thyroid Peroxidase protein with the His tag at the C-terminus has a predicted MW of 90.6 kDa. Due to glycosylation, the protein migrates to 100-115 kDa based on Bis-Tris PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Mouse Thyroid Peroxidase Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Mouse Thyroid Peroxidase Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Mouse Thyroid Peroxidase Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004450: Mouse Thyroid Peroxidase Protein with the C-His Tag (小鼠甲状腺过氧化物酶蛋白 C-His 标签)
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune thyroid disease, for example, the expression of thyroid peroxidase is lost in papillary thyroid carcinoma.
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