Mouse LAG3/CD223 Protein C-His Tag | Syd Labs BP005659

Mouse LAG3/CD223 Protein BP005659 Syd Labs

Mouse LAG3/CD223 Protein C-His Tag | Syd Labs BP005659

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(悉得)Syd Labs 货号:BP005659 Mouse LAG3/CD223 Protein with the C-His Tag (小鼠 LAG3/CD223 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Leu442.

SKU: BP005659 分类: ,

产品参数

货号 BP005659
产品名称Mouse LAG3/CD223 Protein C-His Tag | Syd Labs BP005659
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CD223; FDC; LAG3; LAG-3; sLAG-3
物种 Mouse
来源 The recombinant Mouse LAG3/CD223 Protein, (amino acids Ser23-Leu442) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Accession Q61790
产品标签 C-His
生物素化 no
确定序列 Ser23-Leu442
分子量 The recombinant Mouse LAG3/CD223 protein with the His tag at the C-terminus has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Mouse LAG3 protein with the C-His tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Mouse FGL1 protein with the C-hFc tag with the EC50 of 0.18 ug/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Mouse LAG3/CD223 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Mouse LAG3/CD223 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Mouse LAG3/CD223 Protein performance should be determined experimentally by the investigator.
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文献

BP005659: Mouse LAG3/CD223 Protein with the C-His Tag (小鼠 LAG3/CD223 蛋白 C-His 标签)

 

LAG-3, is a protein which in humans is encoded by the LAG3 gene, which is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders.

请记住我们的产品信息: 小鼠 LAG3/CD223 蛋白 (C-His 标签)BP005659 Syd Labs(Mouse LAG3/CD223 Protein with the C-His Tag).