Mouse IL-17RB Protein C-His Tag | Syd Labs BP004790
(悉得）Syd Labs 货号：BP004790 Mouse IL-17RB Protein with the C-His Tag (小鼠 IL-17RB 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.
产品参数
| 货号 | BP004790 |
|---|---|
| 产品名称 | Mouse IL-17RB Protein C-His Tag | Syd Labs BP004790 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB |
| 物种 | Mouse |
| 来源 | The recombinant Mouse IL-17RB Protein, (amino acids Arg18-Gly286) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | Q9JIP3-1 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Arg18-Gly286 |
| 分子量 | The recombinant Mouse IL-17RB protein with the His tag at the C-terminus has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Mouse IL-17RB Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Mouse IL-17RB Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Mouse IL-17RB Protein performance should be determined experimentally by the investigator. |
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文献
BP004790: Mouse IL-17RB Protein with the C-His Tag (小鼠 IL-17RB 蛋白 C-His 标签)
Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.
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