Mouse IL-17R alpha/CD217 Protein C-hFc Tag | Syd Labs BP004306
(悉得）Syd Labs 货号：BP004306 Mouse IL-17R alpha/CD217 Protein with the C-hFc Tag (小鼠 IL-17R α/CD217 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser32-Trp322.
产品参数
| 货号 | BP004306 |
|---|---|
| 产品名称 | Mouse IL-17R alpha/CD217 Protein C-hFc Tag | Syd Labs BP004306 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-7R; IL-7R-alpha; ILRA |
| 物种 | Mouse |
| 来源 | The recombinant Mouse IL-17R alpha/CD217 Protein, (amino acids Ser32-Trp322) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | Q60943 |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Ser32-Trp322 |
| 分子量 | The recombinant Mouse IL-17R alpha/CD217 protein with the hFc tag at the C-terminus has a predicted MW of 60.1 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Mouse IL-17A&F protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Mouse IL-17R alpha protein with the C-hFc tag with the EC50 of 35.9 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Mouse IL-17R alpha/CD217 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1EU per ug by the LAL method. |
| 运输 | The recombinant Mouse IL-17R alpha/CD217 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Mouse IL-17R alpha/CD217 Protein performance should be determined experimentally by the investigator. |
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文献
BP004306: Mouse IL-17R alpha/CD217 Protein with the C-hFc Tag (小鼠 IL-17R α/CD217 蛋白 C-hFc 标签)
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
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