Mouse FcRn Protein C-His Tag | Syd Labs BP004300
(悉得）Syd Labs 货号：BP004300 Mouse FcRn Protein with the C-His Tag (小鼠 FcRn 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-Ser297 (FCGRT)&Ile21-Met119 (B2M).
产品参数
| 货号 | BP004300 |
|---|---|
| 产品名称 | Mouse FcRn Protein C-His Tag | Syd Labs BP004300 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | FcRn alpha chain; FCGRT; FCRN; FCGRT&B2M |
| 物种 | Mouse |
| 来源 | The recombinant Mouse FcRn Protein, (amino acids Ser22-Ser297(FCGRT) & Ile21-Met119(B2M)) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | Q61559(FCGRT)&P01887(B2M) |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Ser22-Ser297(FCGRT) & Ile21-Met119(B2M) |
| 分子量 | The recombinant Mouse FcRn protein with the His tag at the C-terminus has a predicted MW of 32.1 kDa (FCGRT)&11.7 kDa (B2M). Due to glycosylation, the protein migrates to 50-55 kDa (FCGRT)&14-15 kDa (B2M) based on Tris-Bis PAGE result. |
| 活性 | The affinity constant of 1.76 nM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Mouse FcRn Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1EU per ug by the LAL method. |
| 运输 | The recombinant Mouse FcRn Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Mouse FcRn Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004300: Mouse FcRn Protein with the C-His Tag (小鼠 FcRn 蛋白 C-His 标签)
The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
请记住我们的产品信息: 小鼠 FcRn 蛋白 （C-His 标签）BP004300 Syd Labs（Mouse FcRn Protein with the C-His Tag）.