MGMT Rabbit mAb
MGMT; O-6-methylguanine-DNA methyltransferase
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| 货号 | A11151 |
|---|---|
| 产品名称 | MGMT Rabbit mAb |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | 悉得（Syd Labs） |
| 别称 | MGMT; O-6-methylguanine-DNA methyltransferase |
| 基因名称 | MGMT |
| 蛋白名 | MGMT |
| Uniprot/Swissprot ID | P16455 |
| Entrez GeneID | 4255 |
| 克隆号 | ARC0529 |
| 克隆性 | Monoclonal |
| 来源 | Rabbit |
| 反应性 | Human |
| 偶联 | Unconjugated |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com |
描述
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.
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