抑制剂，激活剂，拮抗剂和激动剂

Lorlatinib (PF-06463922) (CAS No.: 1454846-35-5) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor. It has Kis of <0.025 nM, <0.07 nM, and 0.7 nM for ROS1, wild type ALK,…