Background Information:

PD-0325901 is a potent and highly selective small molecule MEK
(MAPK/ERK Kinase) inhibitor with a Ki at low nM, displays better
bioavailability, stability and superior pharmacokinetic property than
CI-1040, a first generation MEK inhibitor.

Reference:

1. Barrett, SD et al. “The discovery of the benzhydroxamine MEK
inhibitors CI-1040 and PD 0325901” Bioorg. Med. Chem. Lett. 2008, 18,
6501-6504.

APIM050221: PD-0325901

CAS No.: 391210-10-9.
Molecular Formula: C₁₆H₁₄F₃IN₂O_4.
Molecular Weight: 482.2.
Purity: >99.5% (achiral HPLC at 214 and 254 nm), 100% optical purity (chiral HPLC).
QC: Achiral HPLC, Chiral HPLC, ¹HNMR, Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.