Human TRAIL R2/DR5/TNFRSF10B Protein C-His-Avi Tag | Syd Labs BP005541

Human TRAIL R2/DR5/TNFRSF10B Protein BP005541 Syd Labs

Human TRAIL R2/DR5/TNFRSF10B Protein C-His-Avi Tag | Syd Labs BP005541

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(悉得)Syd Labs 货号:BP005541 Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag (人 TRAIL R2/DR5/TNFRSF10B 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ile56-Glu182.

SKU: BP005541 分类: ,

产品参数

货号 BP005541
产品名称Human TRAIL R2/DR5/TNFRSF10B Protein C-His-Avi Tag | Syd Labs BP005541
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER
物种 Human
来源 The recombinant Human TRAIL R2/DR5/TNFRSF10B Protein, (amino acids Ile56-Glu182) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Accession O14763-1
产品标签 C-His-Avi
生物素化 no
确定序列 Ile56-Glu182
分子量 The recombinant Human TRAIL R2/DR5/TNFRSF10B protein with the His-Avi tag at the C-terminus has a predicted MW of 17.2 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human TRAIL R2 protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-TRAIL R2 Antibody protein with the C-hFc tag with the EC50 of 8.5 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human TRAIL R2/DR5/TNFRSF10B Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human TRAIL R2/DR5/TNFRSF10B Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human TRAIL R2/DR5/TNFRSF10B Protein performance should be determined experimentally by the investigator.
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文献

BP005541: Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag (人 TRAIL R2/DR5/TNFRSF10B 蛋白 C-His-Avi 标签)

DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
请记住我们的产品信息: 人 TRAIL R2/DR5/TNFRSF10B 蛋白 (C-His-Avi 标签)BP005541 Syd Labs(Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag).