Human SIGIRR Protein C-hFc Tag | Syd Labs BP003245

Human SIGIRR Protein BP003245 Syd Labs

Human SIGIRR Protein C-hFc Tag | Syd Labs BP003245

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(悉得)Syd Labs 货号:BP003245 Human SIGIRR Protein with the C-hFc Tag (人 SIGIRR 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-terminal.It contains Met1-His118.

SKU: BP003245 分类: ,

产品参数

货号 BP003245
产品名称Human SIGIRR Protein C-hFc Tag | Syd Labs BP003245
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
物种 Human
来源 The recombinant Human SIGIRR Protein, (amino acids Met1-His118) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Accession Q6IA17-1
产品标签 C-hFc
生物素化 no
确定序列 Met1-His118
分子量 The recombinant Human SIGIRR protein with the hFc tag at the C-terminus has a predicted MW of 39.29 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
Form Liquid
形式 Supplied as 0.22μm filtered solution in PBS (pH 7.4).
制剂 It is recommended to reconstitute the lyophilized recombinant Human SIGIRR Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human SIGIRR Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human SIGIRR Protein performance should be determined experimentally by the investigator.
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BP003245: Human SIGIRR Protein with the C-hFc Tag (人 SIGIRR 蛋白 C-hFc 标签)

TIR8, also known as single Ig IL-1-related receptor, is a member of the IL-1 receptor/Toll-like receptor (TLR) superfamily, which acts as an intracellular decoy for components of the signaling pathway. Structurally, it is characterized by a single extracellular Ig domain, an intracellular TIR domain and 95-aa cytoplasmic tail. Recently, TIR8 was shown to inhibit NF-B activation by members of the IL-1/TLR family. The inhibitory activity of TIR8 was associated with trapping of TRAF6 and IRAK1.
请记住我们的产品信息: 人 SIGIRR 蛋白 (C-hFc 标签)BP003245 Syd Labs(Human SIGIRR Protein with the C-hFc Tag).