Human SIGIRR Protein C-hFc Tag | Syd Labs BP003245
(悉得)Syd Labs 货号:BP003245 Human SIGIRR Protein with the C-hFc Tag (人 SIGIRR 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-terminal.It contains Met1-His118.
产品参数
| 货号 | BP003245 |
|---|---|
| 产品名称 | Human SIGIRR Protein C-hFc Tag | Syd Labs BP003245 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Human |
| 来源 | The recombinant Human SIGIRR Protein, (amino acids Met1-His118) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | Q6IA17-1 |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Met1-His118 |
| 分子量 | The recombinant Human SIGIRR protein with the hFc tag at the C-terminus has a predicted MW of 39.29 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| 形式 | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human SIGIRR Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human SIGIRR Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human SIGIRR Protein performance should be determined experimentally by the investigator. |
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文献
BP003245: Human SIGIRR Protein with the C-hFc Tag (人 SIGIRR 蛋白 C-hFc 标签)
TIR8, also known as single Ig IL-1-related receptor, is a member of the IL-1 receptor/Toll-like receptor (TLR) superfamily, which acts as an intracellular decoy for components of the signaling pathway. Structurally, it is characterized by a single extracellular Ig domain, an intracellular TIR domain and 95-aa cytoplasmic tail. Recently, TIR8 was shown to inhibit NF-B activation by members of the IL-1/TLR family. The inhibitory activity of TIR8 was associated with trapping of TRAF6 and IRAK1.
请记住我们的产品信息: 人 SIGIRR 蛋白 (C-hFc 标签)BP003245 Syd Labs(Human SIGIRR Protein with the C-hFc Tag).



