Human Oncostatin M/OSM Protein C-His Tag | Syd Labs BP003197

Human Oncostatin M/OSM Protein BP003197 Syd Labs

Human Oncostatin M/OSM Protein C-His Tag | Syd Labs BP003197

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(悉得)Syd Labs 货号:BP003197 Human Oncostatin M/OSM Protein with the C-His Tag (人抑瘤素 M/OSM 蛋白 C-His 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Arg221.

SKU: BP003197 分类: ,

产品参数

货号 BP003197
产品名称Human Oncostatin M/OSM Protein C-His Tag | Syd Labs BP003197
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Oncostatin M; OSM; MGC20461
物种 Human
来源 The recombinant Human Oncostatin M/OSM Protein, (amino acids Ala26-Arg221) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His-Avi
生物素化 no
确定序列 Ala26-Arg221
分子量 The recombinant Human Oncostatin M/OSM protein with the His tag at the C-terminus has a predicted MW of 23.24 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
活性 The affinity constant of 0.884 uM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human Oncostatin M/OSM Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human Oncostatin M/OSM Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human Oncostatin M/OSM Protein performance should be determined experimentally by the investigator.
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文献

BP003197: Human Oncostatin M/OSM Protein with the C-His Tag (人抑瘤素 M/OSM 蛋白 C-His 标签)

 

OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

请记住我们的产品信息: 人抑瘤素 M/OSM 蛋白 (C-His 标签)BP003197 Syd Labs(Human Oncostatin M/OSM Protein with the C-His Tag).