Human LGR-5 Protein BP003929 Syd Labs
Human LGR-5 Protein (LGR-HM205)
Human LGR-5 Protein (LGR-HM205)
Human LGR-5 Protein BP003929 Syd Labs
Human LGR-5 Protein (LGR-HM205)
Human LGR-5 Protein (LGR-HM205)

Human LGR-5 Protein C-hFc Tag | Syd Labs BP003929

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Proteinase K Solution, PCR Grade (20 mg/ml): MB112 Syd Labs Proteinase K Solution, PCR Grade (20 mg/ml)
Human LGR-5 Protein BP003929 Syd Labs

Human LGR-5 Protein C-hFc Tag | Syd Labs BP003929

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(悉得）Syd Labs 货号：BP003929 Human LGR-5 Protein with the C-hFc Tag (人 LGR-5 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly22-Pro543.

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Syd Labs, Inc.
SKU： BP003929 分类： ,

产品参数

货号 BP003929
产品名称Human LGR-5 Protein C-hFc Tag | Syd Labs BP003929
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
物种 Human
来源 The recombinant Human LGR-5 Protein, (amino acids Gly22-Pro543) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Accession O75473-1
产品标签 C-hFc
生物素化 no
确定序列 Gly22-Pro543
分子量 The recombinant Human LGR-5 protein with the hFc tag at the C-terminus has a predicted MW of 85 kDa. Due to glycosylation, the protein migrates to 110-120 kDa based on Tris-Bis PAGE result.
活性 The affinity constant of 0.59 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS, 5mM DTT (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human LGR-5 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human LGR-5 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human LGR-5 Protein performance should be determined experimentally by the investigator.
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文献

BP003929: Human LGR-5 Protein with the C-hFc Tag (人 LGR-5 蛋白 C-hFc 标签)

 

G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma.

请记住我们的产品信息: 人 LGR-5 蛋白 （C-hFc 标签）BP003929 Syd Labs（Human LGR-5 Protein with the C-hFc Tag）.