Human JAM-A Protein BP004870 Syd Labs
Human JAM-A Protein (JAM-HM10A)
Human JAM-A Protein BP004870 Syd Labs
Human JAM-A Protein (JAM-HM10A)

Human JAM-A Protein C-His Tag | Syd Labs BP004870

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Human JAM-A Protein BP004870 Syd Labs

Human JAM-A Protein C-His Tag | Syd Labs BP004870

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(悉得）Syd Labs 货号：BP004870 Human JAM-A Protein with the C-His Tag (人 JAM-A 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser28-Val238.

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Syd Labs, Inc.
SKU： BP004870 分类： ,

产品参数

货号 BP004870
产品名称Human JAM-A Protein C-His Tag | Syd Labs BP004870
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 JAM-A; JAM-1; CD321; JAM; JCAM; JCAM1; KAT; PAM-1; F11 receptor; F11R; PAM-1KAT
物种 Human
来源 The recombinant Human JAM-A Protein, (amino acids Ser28-Val238.) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Accession Q9Y624-1
产品标签 C-His
生物素化 no
确定序列 Ser28-Val238.
分子量 The recombinant Human JAM-A protein with the His tag at the C-terminus has a predicted MW of 24 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human JAM-A protein with the C-His tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-JAM-A Antibody protein with the C-hFc tag with the EC50 of 2.4 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human JAM-A Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human JAM-A Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human JAM-A Protein performance should be determined experimentally by the investigator.
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文献

BP004870: Human JAM-A Protein with the C-His Tag (人 JAM-A 蛋白 C-His 标签)

 

junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.

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