Human IL-31 RA Protein BP004910 Syd Labs
Human IL-31 RA Protein (ILR-HM2RA)
Human IL-31 RA Protein (ILR-HM2RA)
Human IL-31 RA Protein (ILR-HM2RA)
Human IL-31 RA Protein BP004910 Syd Labs
Human IL-31 RA Protein (ILR-HM2RA)
Human IL-31 RA Protein (ILR-HM2RA)
Human IL-31 RA Protein (ILR-HM2RA)

Human IL-31 RA Protein C-hFc Tag | Syd Labs BP004910

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Human IL-31 RA Protein BP004910 Syd Labs

Human IL-31 RA Protein C-hFc Tag | Syd Labs BP004910

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(悉得）Syd Labs 货号：BP004910 Human IL-31 RA Protein with the C-hFc Tag (人 IL-31 RA 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala20-Glu519.

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SKU： BP004910 分类： ,

产品参数

货号 BP004910
产品名称Human IL-31 RA Protein C-hFc Tag | Syd Labs BP004910
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 IL-31RA; IL-31R-alpha; Gp130-like receptor; CRL3; GPL; ZcytoR17; GLM-R; CRL3Glmr; GLM-RMGC125346; PRO21384
物种 Human
来源 The recombinant Human IL-31 RA Protein, (amino acids Ala20-Glu519) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Accession Q8NI17-1
产品标签 C-hFc
生物素化 no
确定序列 Ala20-Glu519
分子量 The recombinant Human IL-31 RA protein with the hFc tag at the C-terminus has a predicted MW of 83.8 kDa. Due to glycosylation, the protein migrates to 110-135 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human IL-31 protein with the C-hFc tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human IL-31 RA protein with the C-hFc tag with the EC50 of 1.53 ug/ml determined by ELISA (QC Test). The affinity constant of 1.5 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human IL-31 RA Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human IL-31 RA Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human IL-31 RA Protein performance should be determined experimentally by the investigator.
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文献

BP004910: Human IL-31 RA Protein with the C-hFc Tag (人 IL-31 RA 蛋白 C-hFc 标签)

 

Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs).IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.

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