Human IFN gamma R1/IFNGR1 Protein C-hFc Tag | Syd Labs BP005091

Human IFN gamma R1/IFNGR1 Protein BP005091 Syd Labs

Human IFN gamma R1/IFNGR1 Protein C-hFc Tag | Syd Labs BP005091

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(悉得)Syd Labs 货号:BP005091 Human IFN gamma R1/IFNGR1 Protein with the C-hFc Tag (人 IFN γ R1/IFNGR1 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.

货号 BP005091
产品名称Human IFN gamma R1/IFNGR1 Protein C-hFc Tag | Syd Labs BP005091
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 IFN-gamma-R1; CDw119; CD119; IFNGR1; IFNGR; AVP; FLJ45734; IFN-gamma R1; IFN-gR1; type 2
物种 Human
来源 The recombinant Human IFN gamma R1/IFNGR1 Protein, (amino acids Glu18-Gly245) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Accession AAH05333
产品标签 C-hFc
生物素化 no
确定序列 Glu18-Gly245
分子量 The recombinant Human IFN gamma R1/IFNGR1 protein with the hFc tag at the C-terminus has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human IFN gamma protein with the C-hFc tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human IFN gamma R1 protein with the C-hFc tag with the EC50 of 2.8 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human IFN gamma R1/IFNGR1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human IFN gamma R1/IFNGR1 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human IFN gamma R1/IFNGR1 Protein performance should be determined experimentally by the investigator.
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描述

BP005091: Human IFN gamma R1/IFNGR1 Protein with the C-hFc Tag (人 IFN γ R1/IFNGR1 蛋白 C-hFc 标签)

 

IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.

请记住我们的产品信息: 人 IFN γ R1/IFNGR1 蛋白 (C-hFc 标签)BP005091 Syd Labs(Human IFN gamma R1/IFNGR1 Protein with the C-hFc Tag).

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