Human GPRC5D Protein-VLP BP005191 Syd Labs
Human GPRC5D Protein-VLP (GPR-HM05P)
Human GPRC5D Protein-VLP BP005191 Syd Labs
Human GPRC5D Protein-VLP (GPR-HM05P)

Human GPRC5D Protein-VLP | Syd Labs BP005191

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Human GPRC5D Protein-VLP BP005191 Syd Labs

Human GPRC5D Protein-VLP | Syd Labs BP005191

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(悉得）Syd Labs 货号：BP005191 Human GPRC5D Protein-VLP (人 GPRC5D 蛋白-VLP) is expressed from HEK293.It contains Met1-Val345.

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SKU： BP005191 分类： ,

产品参数

货号 BP005191
产品名称Human GPRC5D Protein-VLP | Syd Labs BP005191
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
物种 Human
来源 The recombinant Human GPRC5D Protein-VLP, (amino acids Met1-Val345) , was produced in HEK 293 cells.
生物素化 no
确定序列 Met1-Val345
分子量 The recombinant Human GPRC5D Protein-VLP protein has a predicted MW of 39.6 kDa.
活性 Immobilized recombinant Human GPRC5D VLP at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-GPRC5D Antibody, hFc tag with the EC50 of 3.8 ng/ml determined by ELISA.
Form Liquid
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human GPRC5D Protein-VLP in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human GPRC5D Protein-VLP is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human GPRC5D Protein-VLP performance should be determined experimentally by the investigator.
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文献

BP005191: Human GPRC5D Protein-VLP (人 GPRC5D 蛋白-VLP)

 

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

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