Human GITR/TNFRSF18 Protein C-His Tag | Syd Labs BP005385
(悉得）Syd Labs 货号：BP005385 Human GITR/TNFRSF18 Protein with the C-His Tag (人 GITR/TNFRSF18 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln26-Glu161.
产品参数
| 货号 | BP005385 |
|---|---|
| 产品名称 | Human GITR/TNFRSF18 Protein C-His Tag | Syd Labs BP005385 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD357; GITR; GITR-D; TNFRSF18; AITR |
| 物种 | Human |
| 来源 | The recombinant Human GITR/TNFRSF18 Protein, (amino acids Gln26-Glu161) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gln26-Glu161 |
| 分子量 | The recombinant Human GITR/TNFRSF18 protein with the His tag at the C-terminus has a predicted MW of 15.4 kDa. Due to glycosylation, the protein migrates to 25-28 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human GITR Ligand Trimer protein with the C-His tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human GITR protein with the C-His tag with the EC50 of 2.60 ug/ml determined by ELISA (QC Test). The affinity constant of 4.47 nM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human GITR/TNFRSF18 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human GITR/TNFRSF18 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human GITR/TNFRSF18 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005385: Human GITR/TNFRSF18 Protein with the C-His Tag (人 GITR/TNFRSF18 蛋白 C-His 标签)
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
请记住我们的产品信息: 人 GITR/TNFRSF18 蛋白 （C-His 标签）BP005385 Syd Labs（Human GITR/TNFRSF18 Protein with the C-His Tag）.
