Human GITR/TNFRSF18 Protein BP004792 Syd Labs
Human GITR/TNFRSF18 Protein (GTR-HM201)
Human GITR/TNFRSF18 Protein (GTR-HM201)
Human GITR/TNFRSF18 Protein BP004792 Syd Labs
Human GITR/TNFRSF18 Protein (GTR-HM201)
Human GITR/TNFRSF18 Protein (GTR-HM201)

Human GITR/TNFRSF18 Protein C-hFc Tag | Syd Labs BP004792

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Human GITR/TNFRSF18 Protein BP004792 Syd Labs

Human GITR/TNFRSF18 Protein C-hFc Tag | Syd Labs BP004792

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(悉得）Syd Labs 货号：BP004792 Human GITR/TNFRSF18 Protein with the C-hFc Tag (人 GITR/TNFRSF18 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Glu161.

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SKU： BP004792 分类： ,

产品参数

货号 BP004792
产品名称Human GITR/TNFRSF18 Protein C-hFc Tag | Syd Labs BP004792
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CD357; GITR; GITR-D; TNFRSF18; AITR
物种 Human
来源 The recombinant Human GITR/TNFRSF18 Protein, (amino acids Gln26-Glu161) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-hFc
生物素化 no
确定序列 Gln26-Glu161
分子量 The recombinant Human GITR/TNFRSF18 protein with the hFc tag at the C-terminus has a predicted MW of 41.3 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human GITR Ligand Trimer protein with the C-hFc tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human GITR protein with the C-hFc tag with the EC50 of 0.44 ug/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human GITR/TNFRSF18 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human GITR/TNFRSF18 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human GITR/TNFRSF18 Protein performance should be determined experimentally by the investigator.
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文献

BP004792: Human GITR/TNFRSF18 Protein with the C-hFc Tag (人 GITR/TNFRSF18 蛋白 C-hFc 标签)

 

GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

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