Human FOLR4/Juno Protein C-His Tag | Syd Labs BP004323
(悉得）Syd Labs 货号：BP004323 Human FOLR4/Juno Protein with the C-His Tag (人 FOLR4/Juno 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly20-Ser228.
产品参数
| 货号 | BP004323 |
|---|---|
| 产品名称 | Human FOLR4/Juno Protein C-His Tag | Syd Labs BP004323 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | Folate receptor 4; FR-delta; Izumo1r; Folbp3; Juno; FOLR4, LOC390243 |
| 物种 | Human |
| 来源 | The recombinant Human FOLR4/Juno Protein, (amino acids Gly20-Ser228) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gly20-Ser228 |
| 分子量 | The recombinant Human FOLR4/Juno protein with the His tag at the C-terminus has a predicted MW of 25 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human FOLR4/Juno Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human FOLR4/Juno Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human FOLR4/Juno Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004323: Human FOLR4/Juno Protein with the C-His Tag (人 FOLR4/Juno 蛋白 C-His 标签)
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno’s presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor.
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