Human EREG Protein BP004586 Syd Labs
Human EREG Protein (ERE-HM201)
Human EREG Protein BP004586 Syd Labs
Human EREG Protein (ERE-HM201)

Human EREG Protein N-hFc Tag | Syd Labs BP004586

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) BP003971 Syd Labs Biotinylated Cynomolgus PADI4 Protein N-His Tag (Primary Amine Labeling) | Syd Labs BP003971
Proteinase K Solution, PCR Grade (20 mg/ml): MB112 Syd Labs Proteinase K Solution, PCR Grade (20 mg/ml)
Human EREG Protein BP004586 Syd Labs

Human EREG Protein N-hFc Tag | Syd Labs BP004586

In stock

一键复制

(悉得）Syd Labs 货号：BP004586 Human EREG Protein with the N-hFc Tag (人 EREG 蛋白 N-hFc 标签) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val63-Leu108.

Store
Syd Labs, Inc.
SKU： BP004586 分类： ,

产品参数

货号 BP004586
产品名称Human EREG Protein N-hFc Tag | Syd Labs BP004586
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Proepiregulin; EPR; Epiregulin; EREG; ER
物种 Human
来源 The recombinant Human EREG Protein, (amino acids Val63-Leu108) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
产品标签 N-hFc
生物素化 no
确定序列 Val63-Leu108
分子量 The recombinant Human EREG protein with the hFc tag at the N-terminus has a predicted MW of 32.6 kDa. Due to glycosylation, the protein migrates to 37-42 kDa based on Tris-Bis PAGE result.
Form Liquid
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human EREG Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human EREG Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human EREG Protein performance should be determined experimentally by the investigator.
产品咨询 Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。
关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理）

文献

BP004586: Human EREG Protein with the N-hFc Tag (人 EREG 蛋白 N-hFc 标签)

 

Epidermal growth factor receptor (EGFR) regulates many crucial cellular programs, with seven different activating ligands shaping cell signaling in distinct ways.EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. As a consequence, EREG or EPGN induce less stable EGFR dimers than EGF-making them partial agonists of EGFR dimerization. Unexpectedly, this weakened dimerization elicits more sustained EGFR signaling than seen with EGF, provoking responses in breast cancer cells associated with differentiation rather than proliferation.

请记住我们的产品信息: 人 EREG 蛋白（N-hFc 标签）BP004586 Syd Labs（Human EREG Protein with the N-hFc Tag）.