Human CXCL13/BCA-1 Protein N-His-Sumo Tag | Syd Labs BP004083
(悉得）Syd Labs 货号：BP004083 Human CXCL13/BCA-1 Protein with the N-His-Sumo Tag (人 CXCL13/BCA-1 蛋白 N-His-Sumo 标签) is expressed from E.coli with His tag and Sumo tag at the N-Terminus.It contains Val23-Pro109.
产品参数
| 货号 | BP004083 |
|---|---|
| 产品名称 | Human CXCL13/BCA-1 Protein N-His-Sumo Tag | Syd Labs BP004083 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Human |
| 来源 | The recombinant Human CXCL13/BCA-1 Protein, (amino acids Val23-Pro109) fused with a His-Sumo tag at the N-terminus, was produced in E.coli cells. |
| Accession | O43927 |
| 产品标签 | N-His-Sumo |
| 生物素化 | no |
| 确定序列 | Val23-Pro109 |
| 分子量 | The recombinant Human CXCL13/BCA-1 protein with the His-Sumo tag at the N-terminus has a predicted MW of 22.9 kDa. The protein migrates to 26-28 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Anti-CXCL13 Antibody protein with the N-His-Sumo at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human CXCL13 protein with the N-His tag with the EC50 of 0.54 ug/ml determined by ELISA. |
| Form | Liquid |
| 形式 | Supplied as 0.22μm filtered solution in 0.1M Glycine, 0.3M NaCl, 0.2M L-arginine, 10% Glycerol (pH 3.0). |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human CXCL13/BCA-1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human CXCL13/BCA-1 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human CXCL13/BCA-1 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004083: Human CXCL13/BCA-1 Protein with the N-His-Sumo Tag (人 CXCL13/BCA-1 蛋白 N-His-Sumo 标签)
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
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